United States securities and exchange commission logo March 5, 2024 Yajing Chen Chief Financial Officer Zai Lab Ltd 4560 Jinke Road Bldg. 1, Fourth Floor Pudong, Shanghai, China 201210 Re: Zai Lab Ltd Form 10-K for Fiscal Year Ended December 31, 2022 File No. 001-38205 Dear Yajing Chen: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Disclosure Review Program cc: Aslynn Hogue